Paul W. Franks, UMEA

Associated Professor Paul W. Franks

Role and contribution

Professor Franks is deputy lead of workpackage 2.6 and contributes to WP3.1 and 3.4 and in WP1.7 where he leads the analyses on gene-physical activity interaction.

Scientific profile

Professor Franks is involved in studies to determine the role of genetic variation and physical activity energy expenditure in the development of type 2 diabetes. He is a co investigator on a large clinical trial in which the interaction between genetic variation and lifestyle intervention on diabetes incidence is being assessed (Diabetes Prevention Program; PI: D Altshuler, Harvard) and is the Principal Investigator on planned experimental studies of energy balance, gene expression and insulin sensitivity. Whilst based at the US National Institutes of Health, Prof Franks was the Principal Investigator on studies of energy expenditure in Navajo Indians and the Responsible Investigator on a large-scale prospective study of gene expression and type 2 diabetes in Pima Indians. He has also worked on observational studies of gene-environment interaction in US and European cohorts.